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Abstract Detail



Emerging infectious diseases by zoosporic parasites

James, Timothy [1].

Deciphering the current amphibian chytridiomycosis panzootic using genomics.

The disease chytridiomycosis is a major cause of amphibian population declines in disparate locations across the world.  The disease agent, Batrachochytrium dendrobatidis (Bd), is enigmatic, being the only chytrid known to parasitize vertebrates. Early population genetic studies on Bd suggested very low genetic diversity with respect to alleles but not with respect to genotypes. Moreover, essentially no discernable geographic genetic structure had been detected. Genome resequencing studies have recently enabled us to overcome this problem of low variation and explain the sources of genotypic diversity. These sources include wide-ranging ploidy including aneuploidy, mitotic recombination, and rare sexual reproduction. In this talk, I will discuss how genomics can distinguish among various scenarios for the emergence of the panzootic lineage and compare patterns between the panzootic genotypes and the more recently identified lineages that are much more restricted in their distribution. I will also discuss, the various geographic patterns of dispersal inferred from the genomic data and tests of the rate and consequences of LOH using from experimentally evolved populations. 


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1 - University of Michigan, Ecology & Evolutionary Biology, 830 N. University, Ann Arbor, MI, 48103, United States

Keywords:
chytrid
recombination
amphibian disease.

Presentation Type: Symposium or Colloquium Presentation
Session: SY7
Location: Auditorium/Kellogg Hotel and Conference Center
Date: Wednesday, June 11th, 2014
Time: 2:00 PM
Number: SY7003
Abstract ID:220
Candidate for Awards:None


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